Clear-Cell Syringoma

November 2, 2010 by

Syringoma are non-cancerous and harmless tumors that are  believed to arise from eccrine ducts. Clear cell syringomas have a similar clinical presentation as other common syringomas and usually appears as papules  on eyelids, although other sites may also be involved.  The only features that differenciate clear-cell syringoma may be the presence of diabetes mellitus in most of the patients.

They are generally asymptomatic and present as flesh-colored or brown-purple papules.  Research suggest that there is  a high association between diabetes mellitus and clear-cell syringoma.  Although they are clinically similar with other syringomas, their histopathology findings can be confused with metastatic clear cell syringoid carcinoma and balloon cell melanoma. So, to exclude other confusions an immunohistochemical analysis may be required.

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The Truth Behind Syringoma Removal

October 24, 2010 by

Syringoma are harmless small skin-colored or yellowish, firm rounded dermal papules or cyst which are multiple and smaller then 3 mm in diameter. They usually starts in young age and sometimes other family members may also have been affected, but family history is rare. They are more common in women then men. Although most of the lesions are limited to the upper parts of the cheeks and lower eyelids, other common sites include the armpits, abdomen, upper chest, penis, and vulva.

Clinically, syringoma are often confused with milia, sebaceous hyperplasia, lichen planus, eruptive xanthoma, urticaria pigmentosa, or  acne vulgaris or even basal cell skin cancer. So definitive diagnosis is needed with histological examination of the lesion. The characteristic appeareance of skin biopsy under a microscope is used to diagnose it.

Treatment of Syringoma is for cosmetic purpose only as these lesion do not harm. But syringomas of the eyelids and cheeks are often frustrating. Most of the literature suggests using carbon dioxide laser. But no comparative studies and no long-term follow-up studies are available on which to base definitive recommendations for treatment.  Some other  treatment options includes  Surgical excision with  suturing, dermabrasion, electrocautery , Electrodesiccation and curettage, cryosurgery, chemical peeling and oral and topical retinoids. But none of this methods are 100% satisfactory.

There are some reports of successful treatment with carbon dioxide laser for facial syringomas. A  report on dermatology online journal suggests the use of topical atropine to alleviate the pruritus in symptomatic eruptive syringoma. Unfortunately, there is no any standard treatment for widespread syringomas and all surgical treatments might result in scarring. There are many Over the counter medications sold on net that claims to remove syringoma but many unsuccessful results with scar formations are reported so be sure to use at your own risk. As these are harmless lesions so they can be just left if it doesn’t cause you worries.

There are no any proven home remedies for syringoma they have to be treated with special medical procedure so consult your dermatologist before trying to treat yourself. It can also be another disorder resembling like syringoma and may be associated with systemic problems.

If you have any questions regarding  Syringoma you can ask us here: Dermatalk Skin Care Forums

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Vulvar Syringoma

June 29, 2010 by

Vulvar syringomas is relatively less reported then syringomas under eye or syringomas occurring in any other areas. As vulvar syringomas may usually be asymptomatic, they may not be recognized over genitalia. They may just appear on vulva alone or associated with eyelid syringoma or syringomas of other areas.

Vulvar syringomas are usually distributed symmetrically on the labia majoras of women in their third decade. They are usually asymptomatic but may be associated with occasional itching. They may especially be exacerbated during menstruation and summer. The lesions are usually multiple and are small, skin color to yellow to light brown papules which may cause vulvar discomfort and frequent pruritus.

It is important to visit a dermatologist to exclude other popular disease of genitalia. Common disease includes senile angiomas, fox-fordyce disease, condyloma acuminata, steatocystoma multiplex, lymphangioma circumscriptum, lichen simplex chronicus and contact dermatitis, which can easily be differentiated on histopathology. Also, association of similar lesions in other parts of the body may aid in diagnosis

Vulvar Syringoma Treatment

As they are harmless, so treatment is not necessary in case asymptomatic lesions. If the lesions are itchy, taking oral antihistamines might help. In case of severe itching, your doctor may prescribe low to mild potent topical corticosteroids. Potent corticosteroids are not recommended. Topical tretinoin and topical atropine have also been tried in some cases. Studies have indicated that topical steroids and oral antihistamines may not be effective in controlling pruritus in vulvar syringoma.

Several treatment modalities have been tried with fair results, but there are no any effective gold standard methods for complete cure. These may include excision, cryotherapy, carbon dioxide lasers and electro-desiccation. Several researches suggest carbon dioxide to be effective in treating the lesions.

It is necessary to search for a vulvar envolvement if one has facial Syringoma.

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Eruptive syringoma

June 19, 2010 by

Eruptive syringoma is a rare type of syringoma, which are eccrine sweat gland tumours. They are small flesh-coloured papules and usually occurs in successive crops on the anterior body surfaces of women.

Eruptive syringoma usually present before or during puberty. They tends to occur high in asian and African American. Eruptive syringoma may usually occur in the axillae, abdomen and chest with or without face involvement.

Eruptive syringoma are usually asymptomatic but some people may have mild itching. There are non other complains besides cosmetic problem. Generally eruptive syringoma can be diagnosis just my looking the lesion but your doctor might perform a skin biopsy to confirm the case.

The Eruptive syringoma lesion are harmless and usually resolve on its own or in most of the cases remain stable. There is no long term complications but people find it uncomfortable in particular, if it occurs in face or any exposed areas.

The main aim of the treatment of syringoma is to minimize the scarring and prevent the recurrence. There are no any definite treatment modalities recommended, but there are many options like surgical excision, electrocautery, liquid nitrogen cryotherapy, dermabrasion, trichloroacetic acid and carbon dioxide lasers ablation. Oral isotretinoin and topical tretinoin and adapalene have been used but with not much success. The most used successive treatment may be Laser treatment. The most commonly used lasers are super-pulsed carbon dioxide laser and erbium laser.

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Syringomas Under Eye

June 2, 2010 by

Syringomas are small harmless lesions that usually appear under the lower eyelids and sometimes on cheeks. They usually starts in young age and present as small, multiple, soft, skin-color to yellow brown papules. Syringomas are common in women then men. As they are harmless no treatment is required. Treatment of Syringoma is for cosmetic purpose only.

Syringoma under eye is caused due to overgrowth of cells from sweat glands. Syringomas may also run in families. It may also be common in other disease. Report shows that more then 18% of people with Down Syndrome may have syringoma. Diabetes peoples also often have clear cell syringoma.

Sometimes Syringoma may be confused with other skin conditions. In that case your doctor will confirm it by skin biopsy and exclude other possible conditions. If syringoma is confirmed as a diagnosis. You may not need any treatment. But syringoma under eye is often frustrating, so for cosmetic reason it can be removed.

Destruction of syringoma may be simple but scarring and recurrence may be occur. So consult your dermatologist before trying any treatment options for syringoma. Some of the syringoma treatment that are being used may include:

  • Excision of lesion with scalpel, scissors or flexible razor blade.
  • Carbon dioxide or Er:YAG laser treatment.
  • Cryosurgery, which involved freezing the lesion with liquid nitrogen.
  • Cauterization, which involves burning the lesion with a electric needle.
  • Electrodesiccation and curettage.
  • Dermabrasion.
  • Trichloroacetic acid.
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